Preparation of ( )-5,6,7-Trioxygenated Dihydrofiavonols and Evaluation of their Superoxide Radical S

• 作 者: Jing Xu GONG Yu Bin FENG Feng
• 机 构: Department of Traditional Chinese Medicine and Natural Drug Research,The Key Laboratory of Chemistry
• 出 处: 中国化学快报（英文版）
• 发表日期: 2004年期
• 关键词: Dihydroflavonol (±)-5 6 7-trioxygenated-dihydroflavonols total synthesis antioxi

The synthesis of (±)-5, 6, 7-trioxygenated dihydroflavonols was carried out. All synthetic compounds were passed through superoxide radical scavenging activity in vitro.Compounds 1 e and 1 g exhibited significant bioactivity with the inhibitory rates of 68.1% and 80.9% at 40 μg/mL, respectively.