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目的探究肺癌放疗后复发患者用三维适形调强放疗进行再治疗的可行性及临床疗效。方法 62例放疗后复发的肺癌患者,随机分为对照组和观察组,每组31例。对照组给予常规放疗,观察组采用三维适形调强放疗治疗。观察两组患者的近期疗效、不良反应及1年后的生存率。结果观察组患者的近期疗效及1年后的生存率均显著高于对照组,差异有统计学意义(P<0.05),不良反应情况比较,差异无统计学意义(P>0.05)。结论三维适形调强放疗在肺癌放疗后复发患者的治疗中提高了治疗的有效率和疾病的控制率,改善了患者远期的生存情况,值得在临床上推广。
Objective To investigate the feasibility and clinical efficacy of three-dimensional conformal IMRT for re-treatment of patients with recurrent lung cancer after radiotherapy. Methods Sixty-two patients with recurrent lung cancer after radiotherapy were randomly divided into control group and observation group, with 31 cases in each group. Control group received conventional radiotherapy, the observation group using three-dimensional conformal IMRT. The two groups of patients were observed the short-term efficacy, adverse reactions and survival after 1 year. Results The short-term curative effect and the one-year survival rate in the observation group were significantly higher than those in the control group (P <0.05). There was no significant difference in adverse reactions between the observation group and the control group (P> 0.05). Conclusion Three-dimensional conformal IMRT improves the efficiency of treatment and control rate of disease in the treatment of patients with recurrent lung cancer after radiotherapy, which improves the long-term survival of patients and is worthy of clinical promotion.