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目的:探讨血清心锚重复蛋白(CARP)在心房颤动(房颤)中的变化及临床意义。方法:选择房颤组64例和窦性心律(窦律)组60例,采用酶联免疫吸附法(ELISA法)检测入选者血清CARP浓度,并对结果进行统计学分析。结果:房颤组CARP水平高于窦律组[(8.08±1.23)ng/L∶(7.09±1.05)ng/L,P<0.05],持续性房颤亚组CARP水平高于阵发性亚组[(8.24±1.27)ng/L∶(7.83±1.30)ng/L,P<0.05]。结论:房颤患者的血清CARP浓度水平明显增高,血清CARP浓度水平与心房颤动的发生和维持有一定联系。
Objective: To investigate the changes of serum cardiac anchored repeat protein (CARP) in atrial fibrillation (AF) and its clinical significance. Methods: Sixty-four patients with atrial fibrillation (AF) and 60 patients with sinus rhythm (sinus rhythm) were enrolled in this study. Serum CARP levels were determined by enzyme-linked immunosorbent assay (ELISA) and the results were statistically analyzed. Results: The CARP level in atrial fibrillation group was significantly higher than that in sinus rhythm group [(8.08 ± 1.23) ng / L vs (7.09 ± 1.05) ng / L, P <0.05] Group [(8.24 ± 1.27) ng / L: (7.83 ± 1.30) ng / L, P <0.05]. Conclusion: The serum CARP concentration in patients with atrial fibrillation was significantly higher. The level of serum CARP was correlated with the occurrence and maintenance of atrial fibrillation.