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一、经血清流行病学证实,婴儿期麻疹疫苗免疫失败的主要原因是免疫机能不成熟而造成的免疫应答不完善。无论婴儿有无胎传抗体,麻疹疫苗免疫成功率和抗体阳转率均与月龄大小呈正相关(r=0.96～0.94);免疫成功者1年后抗体阴转率与月龄大小呈负相关
First, confirmed by serum epidemiology, the main reason for the immunization failure of infantile measles vaccine is imperfect immune response caused by immature immune function. Immunization success rate and antibody positive rate of measles vaccine were positively correlated with age (r = 0.96 ~ 0.94) regardless of the infant’s presence or absence of fetal antibodies. The antibody negative rate of one year after immunization was negatively correlated with age