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一、发病机制 自身免疫性甲状腺疾病有桥本氏病和巴塞杜氏病,从家族发病率和人类白细胞抗原等检查,可看出这些疾病的发生同其它自身免疫性疾病一样与遗传因素有关。作者提出“平衡理论”(见图1),即病毒感染等外界因子造成机体的免疫监视功能紊乱,在甲状腺发生自身免疫现象。 认为甲状腺上皮细胞膜上的TSH受体的抗体及HTS(人甲状腺刺激素)产生过
First, the pathogenesis of autoimmune thyroid disease Hashimoto’s disease and Barte’s disease, from the family incidence and human leukocyte antigen examination, we can see that the occurrence of these diseases, like other autoimmune diseases and genetic factors. The authors put forward the “balance theory” (see Figure 1), that is, external factors such as virus infection cause the body’s immune surveillance disorder, in the thyroid autoimmune phenomenon. Antibodies to the TSH receptor on the thyroid epithelial membrane and HTS (human thyroid stimulating hormone) are thought to have occurred