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目的:评价头孢地尼与奥硝唑对盆腔炎患者免疫学和血液流变学的影响。方法:选取2014年9月—2015年12月间收治的盆腔炎患者84例作为本次的研究对象,采用计算机随机分组法将其分为常规组与观察组,每组42例;常规组患者给予奥硝唑治疗,观察组患者在常规组基础上加用头孢地尼治疗,评价两组患者治疗后的总有效率、免疫学和血液流变学的影响。结果:两组患者均接受为期2周的药物治疗,治疗前两组患者的IL-1、C-反应蛋白(CRP)、血浆黏度和红细胞压积值经组间比较其差异无统计学意义(P>0.05);治疗2周后观察组患者IL-1、C-反应蛋白、血浆黏度和红细胞压积值均优于常规组(P<0.05);治疗后的总有效率为92.86%高于常规组为69.05%(P<0.05)。结论:采用头孢地尼与奥硝唑治疗盆腔炎患者,能明显改善患者临床症状、免疫学和血液流变学各指标。
Objective: To evaluate the effect of cefdinir and ornidazole on the immunology and hemorheology in patients with pelvic inflammatory disease. Methods: A total of 84 patients with pelvic inflammatory disease who were admitted between September 2014 and December 2015 were selected as the study subjects. The patients were divided into two groups according to the randomization method: 42 cases in each group. The patients in the conventional group Given ornidazole treatment, the observation group patients on the basis of conventional group with cefdinir treatment, evaluation of the two groups of patients after treatment, the total efficiency, immunology and hemorheology. Results: The two groups of patients received two weeks of drug treatment. There was no significant difference in the levels of IL-1, C-reactive protein (CRP), plasma viscosity and hematocrit between the two groups before treatment P> 0.05). After 2 weeks of treatment, the levels of IL-1, C-reactive protein, plasma viscosity and hematocrit in the observation group were better than those in the conventional group (P <0.05); the total effective rate was 92.86% The conventional group was 69.05% (P <0.05). Conclusion: Cefdinir and ornidazole in patients with pelvic inflammatory disease can significantly improve the clinical symptoms, immunological and hemorheological indicators.