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介绍了本实验室几年来对健康的昆明种小鼠胸骨骨髓PCE微核、胎鼠肝血PCE微核和正常人外周血淋巴细胞微核实验的结果,发现各种细胞的微核自然发生率均呈正偏态分布,95%正常上限以百分位数法进行计算比较合适。我们的昆明种小鼠胸骨骨髓PCE微核95%正常上限值为4.37%,胎鼠肝血PCE微核95%正常上限值为5.02%,人外周血淋巴细胞微核95%正常上限值为2.4%。并与部分学者报导的正常值进行了比较,其差异可能由于所用动物的品系、饲养条件、实验方法及实验者正确判断微核的经验不同所致。
The results of micronucleus test on PCU micronuclei, PCE micronuclei and peripheral blood lymphocytes of normal Kunming mice in healthy Kunming mice were introduced in this lab. It was found that the natural frequency of micronuclei of various cells Are positive skewed distribution, 95% of the normal upper limit calculated by the percentile method is more appropriate. Our Kunming mouse sternal bone marrow PCE micronucleus 95% upper limit of normal was 4.37%, fetus liver blood PCE micronucleus 95% normal upper limit of 5.02%, human peripheral blood lymphocyte micronucleus 95 % The normal upper limit is 2.4%. And compared with the normal values reported by some scholars. The differences may be due to the strains of animals used, breeding conditions, experimental methods and experimenters’ correct judgment of micronucleus experience.