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目的观察盐酸利托君与硫酸镁治疗先兆早产的疗效及不良反应,用以指导临床上安全有效的用药。方法选取2011年9月~2013年11月本院收治的先兆早产患者共有126里,随机分为治疗组和对照组两组各有63例,将治疗组采用盐酸利托君与对照组采用硫酸镁的疗效进行比较,观察分析两组患者的临床疗效。结果治疗组疗效明显优于对照组,其中治疗组显效38例(60.32%),总有效率90.48%;对照组显效25例(39.68%),总有效率69.84%。且经过统计学处理差异具有统计学意义(P<0.05)。结论盐酸利托君治疗先兆早产起效快,能够延长孕期、保胎率高,且不良反应比较轻微,因此值得在临床上继续推广应用。
Objective To observe the efficacy and adverse reactions of risoterine hydrochloride and magnesium sulfate in the treatment of threatened preterm labor and to guide the safe and effective medication in clinical practice. Methods A total of 126 patients with threatened preterm birth who were treated in our hospital from September 2011 to November 2013 were randomly divided into treatment group (63 cases) and control group (63 cases). Patients in the treatment group were treated with sulfate and Magnesium efficacy comparison, observation and analysis of the clinical efficacy of two groups of patients. Results The therapeutic effect of the treatment group was obviously better than that of the control group, of which 38 cases (60.32%) were effective in the treatment group and the total effective rate was 90.48%. The control group was markedly effective in 25 cases (39.68%), the total effective rate was 69.84%. And statistically significant difference was statistically significant (P <0.05). Conclusion Rituxel hydrochloride treatment of threatened preterm delivery quick onset, can extend the pregnancy, the high rate of miscarriage, and mild adverse reactions, it is worth continuing to promote the clinical application.