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本文复习9例咽旁间隙多形性唾液腺腺瘤,并阐述有关活检、手术和放疗的处理意见。9例中男女性别与疾患两侧大致相等,年龄27～60, 多无症状或诉咽痛,均有咽部肿块,3例尚于下颌角后下扪及肿块。除1例行传统的全腮腺切除术外,其余行颈外进路摘除肿物,术后接受全肿瘤量放疗。除3例外其余的随访2～10年未见复发。肿物均曾作组织学检查,典型病例见有不同致密度、厚度和完整的纤维包囊,由包埋于不等量的粘液样、粘蛋白或软骨样基质中的增生上皮和肌上皮成分组成。有些区域为分化较高的细胞,上皮呈管状或索状分化或呈未分化的校形细胞团块。某些病例有囊性变;4例发现浆液性腮腺样腺体组织的小病灶,或紧靠纤维包囊,或由少数疏松脂肪结缔组织分隔,1例有早期恶变。目前对本病的发病机理仍有争论,一般认为
This article reviewed 9 cases of pleomorphic salivary adenomas in the parapharyngeal space and elaborated on the treatment of biopsy, surgery and radiotherapy. In 9 cases, gender and illness were roughly equal on both sides. Ages ranged from 27 to 60. They were mostly asymptomatic or complained of sore throat. They all had pharyngeal masses. Three cases were still in the mandibular angle and septum and lumps. Except for one case of conventional full parotidectomy, the rest of the extracerebral approach removed the tumor and received total tumor volume after radiotherapy. With the exception of 3 exceptions, no recurrence was observed for the remaining follow-up of 2 to 10 years. Tumors have been used for histological examination. Typical cases have different density, thickness, and complete fiber cysts. They are composed of different amounts of myxoid, mucin, or cartilage-like proliferating epithelium and myoepithelial components. composition. Some areas are highly differentiated cells with tubular or cord-like epithelial differentiation or undifferentiated shape-like cell mass. In some cases, there was cystic degeneration; 4 cases of serous parotid glandular tissue found small lesions, or close to the fiber capsule, or separated by a small amount of loose connective fat, 1 case of early malignant transformation. At present, there is still controversy over the pathogenesis of this disease, generally considered