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目的调查三明某钢铁厂职工40-60岁人群5年前后高尿酸血症的患病率变化,并与其血脂变化进行比对分析。方法分别收集2005年和2010年在我院体检的上述人群血清尿酸(UA)、甘油三脂(TG)、总胆固醇(TCH)、低密度脂蛋白胆固醇(LDL)、高密度脂蛋白胆固醇(HDL)检测值。结果 2005年高尿酸血症患病率为15.8%,其中男性21.2%,女性6.3%。2010年高尿酸血症患病率24.5%,其中男性32.9%,女性8.3%。同时,高尿酸血症与血尿酸正常人群血脂均值对比有显著差异(P<0.01),高尿酸血症人群的血脂异常率较血尿酸正常人群的血脂异常率高(P<0.01)。结论高尿酸血症患病率有逐年增高趋势,男性尿酸增高比例明显高于女性,同时,高尿酸血症人群血脂异常的发生率明显升高,应引起人们高度重视。
Objective To investigate the prevalence of hyperuricemia in 40-60-year-old workers in a steel plant in Sanming city and compare the changes of hyperuricemia with the changes of its blood fat. Methods The serum uric acid (UA), triglyceride (TG), total cholesterol (TCH), low density lipoprotein cholesterol (LDL), high density lipoprotein cholesterol ) Test value. Results The prevalence of hyperuricemia in 2005 was 15.8%, of which 21.2% were male and 6.3% female. The prevalence of hyperuricemia in 2010 was 24.5%, of which 32.9% were male and 8.3% female. At the same time, the hyperuricemia and serum uric acid in normal population were significantly different (P <0.01). The rate of dyslipidemia in hyperuricemia was higher than that in healthy subjects (P <0.01). Conclusions The prevalence of hyperuricemia is increasing year by year. The increasing rate of uric acid in men is obviously higher than that in women. At the same time, the incidence of dyslipidemia in hyperuricemia is obviously increased, which should be paid more attention.