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目的 为进驻高原部队制定营养卫生保障措施提供资料。方法 Wist大鼠60只,按体重随机均分成缺氧10d组、缺氧20d组和对照组。缺氧组大鼠在7000m人体低压舱内模拟缺氧1.5h,每天1次,连续20d。第10d后缺氧10d组和对照组断头取血、心、肾。20d后缺氧20d组大鼠以同样方式处置。用原子吸收分光光度计测定各种组织的钾钠钙含量。结果 缺氧组血浆和肾脏及心脏组织中钙台量较对照组明显低;钾含量在血浆和肾组织中降低1Jb脏组织中升高。两缺氧组血浆中钠含量较对照组明显高,肾脏组织中明显低。结论 慢性缺氧可使血浆、肾和心组织钙含量降低。
Objective To provide information on establishing nutrition and health protection measures for entering the plateau units. Methods Sixty Wist rats were randomly divided into 10 days hypoxia group, 20 days hypoxia group and control group according to body weight. Rats in hypoxia group were hypoxia simulated in 7000m human low-pressure cabin for 1.5h, once a day for 20 days. 10d after hypoxia 10d group and control group decapitated blood, heart and kidney. After 20 days, rats in hypoxia for 20 days were treated in the same way. The atomic absorption spectrophotometer was used to determine the content of potassium, sodium and calcium in various tissues. Results The amount of calcium in plasma, kidney and heart tissue in hypoxia group was significantly lower than that in control group; the content of potassium in plasma and renal tissue decreased 1Jb in dirty tissue. Sodium levels in the plasma of the two hypoxia groups were significantly higher than those in the control group and significantly lower in the kidney tissue. Conclusion Chronic hypoxia can reduce the content of calcium in plasma, kidney and heart tissue.