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红前期是疟原虫进入宿主的第一个时期,阻断红前期疟原虫的发育,就能够从源头上阻断疟疾的发生和传播,有效的红前期疟疾疫苗对于控制疟疾的发病及阻断疟疾的传播有着重要意义。对红前期免疫机制的深入研究对于合理的红前期亚单位疫苗的设计具有重要的指导意义,本文仅就目前疟原虫红前期适应性免疫相关机制的研究做一综述。
The pre-red stage is the first period in which the malaria parasite enters the host. Blocking the development of the pre-red stage malaria parasite can block the occurrence and spread of malaria at its source. The effective red malaria vaccine can be used to control malaria and prevent malaria The dissemination of great significance. The in-depth study on the immune mechanism of pre-red has important guiding significance for the design of rational pre-subunit vaccine. This article only reviews the current research on the mechanism of adaptive immunity in pre-red stage of malaria.