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目的 :观察新辅助化疗加中药康莱特注射液治疗胃癌的疗效。 方法 :81例胃癌病人行新辅助化疗 ,其中 2 2例行加中药康莱特注射液的新辅助化疗 ,观察临床症状变化、病理变化和T淋巴细胞亚群的变化。 结果 :临床症状改善率75 3% ,组织病理学有效率 6 8 9% ,其中 2例达到显效 (hisCR)。 结论 :胃癌的新辅助化疗能提高胃癌的综合治疗疗效 ,加用小剂量中药康莱特注射液对改善化疗后的免疫功能下降无效。提示对化疗后的免疫功能下降应引起重视。
Objective : To observe the efficacy of neoadjuvant chemotherapy plus Chinese medicine Kanglaite injection in the treatment of gastric cancer. Methods: Ninety-eight patients with gastric cancer were treated with neoadjuvant chemotherapy. Twenty-two of them were treated with neoadjuvant chemotherapy with Kanglaite injection. Changes of clinical symptoms, pathological changes and changes of T lymphocyte subsets were observed. Results: The improvement rate of clinical symptoms was 75 3%, and the histopathological efficiency was 68.9%, of which 2 cases had significant effect (hisCR). Conclusion : Neoadjuvant chemotherapy for gastric cancer can improve the comprehensive curative effect of gastric cancer. The addition of low-dose Chinese Kanglaite Injection has no effect on improving the immune function decline after chemotherapy. Tips should pay attention to the decline in immune function after chemotherapy.