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对于免疫复合物的生理病理学意义已经一致公认,相比之下,它们的检出对于疾病描述和治疗的实用性却存在明显的争议.免疫复合物的形成是浆细胞大规模合成抗体的合理结果.免疫复合物将抗原提呈给吞噬细胞清除;也可将抗原送到淋巴样组织的生发中心,从而引起更强的抗体应答.如果抗原是外来的,上述过程对机体有利;如果是自身抗原,这种由免疫复合物介导的清除将是有害的.
Physiological and pathological significance of immune complexes has been well recognized, in contrast, their detection is clearly controversial for the utility of disease description and treatment, and the formation of immune complexes is reasonable for large-scale synthesis of antibodies in plasma cells As a result, the immunocomplexes present the antigen to the phagocyte for clearance, the antigen can also be delivered to the germinal center of lymphoid tissue, resulting in a stronger antibody response, which is beneficial to the body if the antigen is foreign, Antigens, which are mediated by immune complexes, will be detrimental.