论文部分内容阅读
目的 分析山西省太原市严重急性呼吸系统综合征(SARS)患者及其密切接触者和社区人群中血清SARS抗体水平。方法 采用ELISA方法检测3组人群的SARS特异性抗体,并进行分析比较。结果 SARS患者、密切接触者和社区健康人群的SARS冠状病毒(SARS -CoV)抗体阳性率分别为5 2 0 8% ,4 6 3%和1.88% ,3组人群比较差异有统计学意义;3组人群中不同年龄组及性别间抗体阳性率差异无统计学意义。在密切接触者既往各类接触史中,除“接触时有无洗手”与血清SARS -CoV抗体阳性有关外,未发现其它有关因素。结论 太原SARS病例存在过度诊断现象,密切接触者和普通人群中可能存在SARS的隐性感染。
Objective To analyze the level of serum SARS antibodies in patients with severe acute respiratory syndrome (SARS) and its close contacts and community population in Taiyuan, Shanxi Province. Methods The SARS specific antibodies of three groups were detected by ELISA and analyzed. Results The positive rates of SARS-CoV (SARS-CoV) antibodies in SARS patients, close contacts and community-based healthy people were 52.08%, 46.3% and 1.88%, respectively. There were significant differences among the three groups of patients; 3 No significant difference was found in the positive rate of antibody among different age groups and gender among the groups. In the past history of close contact with all types of contacts, no relevant factors were found except for the presence or absence of handwashing during contact with the positive serum SARS-CoV antibody. Conclusion The diagnosis of SARS in Taiyuan is over diagnosed. Infection with SARS may occur in close contacts and the general population.