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在研究支气管哮喘(BA)患者的免疫障碍时,特别注意单核细胞的功能,因为单核细胞除有免疫调节和抗菌作用以外,还对于强烈的支气管痉挛物质的产生和释放起重要作用。 为研究BA患者外周血单核细胞的聚集活性,检查BA18例,均为男性,年龄27～65岁,处在BA加重期,其中特应性BA7例,对变应原高度敏感,皮肤试验阳性;感染变应性BA5例;混合型BA6例。在入院当天或第二天进行单核细胞聚集活性检测,取静脉血,抗凝,离心分离出单核细胞,用花生四烯酸作致聚剂,用计算机光度计聚集仪检测单核细胞聚集速度和幅度。对照组是12名同龄健康人。
In the study of immune disorders in patients with bronchial asthma (BA), special attention is paid to the function of monocytes as mononuclear cells in addition to immunomodulatory and antimicrobial effects play an important role in the production and release of strong bronchoconstrictor substances. In order to study the aggregation activity of peripheral blood mononuclear cells in patients with BA, BA18 were examined in men, aged 27-65 years, at BA exacerbation stage, of which atopic BA7 cases were highly sensitive to allergen and skin test positive ; Infection of allergic BA5 cases; mixed BA6 cases. On the day of admission or on the second day monocyte aggregation activity test, take venous blood, anticoagulant, mononuclear cells isolated by centrifugation, arachidonic acid as a polymerization agent, monocyte aggregation detected by a computer photometer Speed and magnitude. The control group was 12 healthy people of the same age.