论文部分内容阅读
目的:评价电针联合口服甲钴胺片治疗T2DM合并轻中度腕管综合征(carpal tunnel syndrome, CTS)的疗效。方法:将符合入选标准的80例T2DM合并轻中度CTS患者采用随机数字表法分为2组，每组40例。治疗过程中，2组分别脱落2例，最终各有38例进入疗效统计。全部患者均积极控制血糖，对照组在此基础上口服甲钴胺片，治疗组在对照组基础上电针患侧大陵、内关，连续治疗6周。采用VAS量表评估疼痛程度，采用波士顿腕管问卷调查量表(Bonston Carpal Tunel Questionair, BCTQ)中的症状量表评估临床症状严重程度；应用肌电诱发电位仪检测感觉神经传导速度(sensory conduction velocity, SCV)、感觉神经动作电位(sensory nerve action potential, SNAP)的波幅及远端运动潜伏期(distal motor latency, DML)。评价临床疗效，记录不良事件。结果:治疗组总有效率为81.6%(31/38)、对照组为60.5%(23/38)，2组比较差异有统计学意义(n χ2＝5.094，n P＝0.024)。治疗后，治疗组VAS、BCTQ评分均低于对照组(n t值分别为2.639、2.790，n P值分别为0.010、0.007)；DML[(3.62±0.19)ms比(4.00±0.17)ms，n t＝68.891]低于对照组(n P<0.01)，SCV[(47.36±0.18)m/s比(42.34±0.14)m/s，n t＝97.163]、SNAP[(14.74±0.18)μV比(12.10±0.16)μV，n t＝51.434]高于对照组(n P<0.01)。治疗期间，2组均未发生严重不良事件。n 结论:电针联合口服甲钴胺片可减轻T2DM合并轻中度CTS患者的疼痛程度，改善腕关节症状。“,”Objective:To observe the clinical efficacy of electroacupuncture in the treatment of type 2 diabetes mellitus combined with mild and moderate carpal tunnel syndrome.Methods:Eighty patients with type 2 diabetes mellitus combined with mild to moderate carpal tunnel syndrome were randomly divided into two groups with 40 patients in each group (n n=40). In the course of the treatment, 2 patients in each group dropped out, which means 38 patients in each group were included. All patients were instructed to actively control blood glucose The control group was given Mecobalamin tablets orally, while the treatment group was given electroacupuncture of Daling and Neiguan on the affected side based onthe control group for 6 weeks. The degree of pain was assessed by VAS, and the severity of clinical symptoms was assessed by the symptom scale of Boston carpal tunnel questionnaire (BCTQ). The sensory nerve conduction velocity (SCV), the amplitude of sensory nerve action potential (SNAP) and the distal motor latency (DML) were detected by EMG evoked potential instrument. The clinical efficacy was evaluated and adverse events were recorded.n Results:The total effective rate was 81.6% (31/38) in the treatment group and 60.5% (23/38) in the control group, and the difference was statistically significant (n χ2=5.094, n P=0.024). After the treatment, the scores of VAS and BCTQ in the treatment group were lower than those of the control group (n t=2.639, 2.790, n P=0.010, 0.007); DML (3.62 ± 0.19 msn vs. 4.00 ± 0.17 ms, n t=68.891) in the treatment group was lower than that of the control group (n P<0.01), while SCV (47.36 ± 0.18 m/sn vs. 42.34 ± 0.14 m/s, n t=97.163) and SNAP (14.74 ± 0.18 μV n vs. 12.10 ± 0.16 μV, n t=51.434) in the treatment group were higher than those of the control group (n P<0.01). During the treatment, no serious adverse events occurred in two groups.n Conclusions:Electroacupuncture is safe and effective in the treatment of mild and moderate carpal tunnel syndrome with type 2 diabetes. It can reduce the degree of pain and improve the symptoms of wrist joint.