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目的研究宫颈液基薄层细胞(TCT)检测结果与阴道镜活检病理及宫颈锥形切除病理间的相关性。方法对受检者做宫颈脱落细胞TCT或巴氏涂片检查,细胞学阳性者在阴道镜下活检行病理检查。结果液基细胞学共检出阳性涂片382例,占12.69%;其中意义不明的不典型鳞状上皮细胞(ASCUS)226例,占7.51%;不典型鳞状上皮细胞(ASC-H)8例,占0.26%;意义不明的不典型腺细胞(AGUS)6例占0.20%;低级别鳞状上皮病变(LSIL)110例,占3.65%;高级别鳞状上皮病变(HSIL)20例,占0.66%,鳞癌8例,占0.26%;腺癌4例,占0.13%。细胞学与阴道镜下活组织病理检查诊断的阳性符合率分别如下:癌89%,CINⅢ92%,CINⅡ46%,CINⅠ100%。结论液基细胞学检查联合阴道镜下病理检查宫颈病变敏感性高,准确度强,有利于提高宫颈癌及癌前病变的早期诊断率。
Objective To study the relationship between the results of cervical liquid-based thin-layer cells (TCT) and colposcopy biopsy and the pathology of cervical conization. Methods The subjects were examined by cervical cytology TCT or Pap smear, cytology-positive biopsy colposcopy pathological examination. Results A total of 382 positive smears were detected by liquid-based cytology, accounting for 12.69%. Among them, 226 cases (7.51%) with atypical unclassified squamous cell carcinoma (ASCUS) of unknown significance (ASC-H) 8 6 cases of unknown atypical glandular cells (AGUS) accounted for 0.20%; 110 cases of low grade squamous epithelial lesions (LSIL), accounting for 3.65%; 20 cases of high grade squamous cell carcinoma (HSIL), accounting for 0.26% 0.66%, squamous cell carcinoma in 8 cases, accounting for 0.26%; adenocarcinoma in 4 cases, accounting for 0.13%. The positive coincidence rates of cytology and colposcopic biopsy were as follows: 89% of cancers, 92% of CINs, 46% of CINs, and 100% of CINs. Conclusion liquid-based cytology combined with colposcopic pathological examination of cervical lesions with high sensitivity and accuracy, is conducive to improve the early diagnosis of cervical cancer and precancerous lesions.