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使用抗多药耐药(MDR)的抗体(HyB_(241))探测了急性非淋巴细胞白血病(ANLL)与慢性粒细胞白血病(CGL)患者白血病细胞P-糖蛋白的表现。以流式细胞光度计检测ANLL 25例(活动期20例,缓解期5例);CGL 8例;MDS 4例以及正常对照组6例。以10%作为阳性和阴性的分界。结果如下:20例活动
The anti-multidrug resistance (MDR) antibody (HyB_ (241)) was used to detect the expression of P-glycoprotein in leukemia cells from patients with acute non-lymphoid leukemia (ANLL) and chronic myelogenous leukemia (CGL) Twenty-five ANLLs (20 active and 5 remission) were detected by flow cytometer; 8 CGLs, 4 MDSs and 6 normal controls. With 10% as the positive and negative boundaries. The results are as follows: 20 cases of activity