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目的探讨临床上对小儿支气管肺炎患儿采用布地奈德联合盐酸氨溴索氧驱动雾化吸入治疗方案的疗效性以及安全性。方法 156例支气管肺炎患儿,随机分为对照组和治疗组,每组78例,两组患儿在入院后均给予临床常规的支气管肺炎治疗,对照组在此基础上氧驱动雾化吸入布地奈德,治疗组在对照组基础上给予盐酸氨溴索,对比分析两组患儿临床主要症状改善、消失时间、住院时间以及不良反应等。结果治疗组总有效率97.44%明显优于对照组83.33%,差异具有统计学意义(P<0.05);临床症状改善、消失时间以及住院时间相比于对照组患儿明显缩短,差异均具有统计学意义(P<0.05);两组患者在治疗期间均无不良反应发生(P>0.05)。结论氧驱动雾化吸入布地奈德治疗以及氧驱动雾化吸入布地奈德联合盐酸氨溴索治疗小儿支气管肺炎安全性高均较高,联合疗法更加有效的改善各指标,值得广泛应用于临床。
Objective To investigate the clinical efficacy and safety of budesonide combined with ambroxol hydrochloride atomization inhalation in children with bronchial pneumonia. Methods A total of 156 children with bronchopneumonia were randomly divided into control group and treatment group, 78 cases in each group. Both groups were given routine bronchopneumonia after admission. In the control group, oxygen-driven inhalation cloth Ned, the treatment group on the basis of the control group to give ambroxol hydrochloride, comparative analysis of two groups of children clinical symptoms, disappearance of time, hospital stay, and adverse reactions. Results The total effective rate in treatment group was 97.44%, which was significantly better than that in control group (83.33%), the difference was statistically significant (P <0.05); the clinical symptoms, disappearance time and hospitalization time were significantly shorter than those in control group (P <0.05). No adverse reactions occurred in both groups during the treatment (P> 0.05). Conclusions Oxygen-driven inhalation of budesonide and oxygen-driven inhalation of budesonide combined with ambroxol hydrochloride have a higher safety in children with bronchopneumonia. The combination therapy is more effective in improving the indexes and should be widely used in clinical practice.