重症肌无力临床常用诊断方法分析

• 作 者: 邓丽影 王春芝 张明
• 机 构: 江西医学院二附院
• 出 处: 江西医药
• 发表日期: 1999年03期
• 关键词: 重症肌无力 新斯的明试验 肌疲劳试验 重复神经刺激 症状学诊断 胸腺切除 单纤维肌电图 诊断方法 诊断法 疑难病例

目的评价重症肌无力（ＭＧ）常用诊断方法的临床价值。方法将已确诊的３９例ＭＧ患者的症状学诊断，肌疲劳试验、新斯的明试验、重复神经刺激（ＲＮＳ）结果进行对比分析。结果症状学诊断法阳性率６６７％，肌疲劳试验阳性率７６９％，新斯的明试验阳性率８５７％，ＲＮＳ阳性率８９８％。结论症状学诊断法及肌疲劳试验为临床常用，新斯的明试验特异性最强，疑难病例需加做ＲＮＳ鉴别，四种方法作用互补。

Objective To evaluate the clinical value of commonly used diagnostic methods for myasthenia gravis (MG). Methods The diagnosis of 39 cases of MG patients with symptoms diagnosis, muscle fatigue test, neostigmine test, repeated nerve stimulation (RNS) results were compared. Results The positive rate of symptomatic diagnosis was 667%, the positive rate of muscle fatigue was 769%, the positive rate of neostigmine was 857%, and the positive rate of RNS was 898%. Conclusions Symptom diagnosis and muscle fatigue tests are commonly used clinically. Neostigmine test has the strongest specificity, difficult cases need to be identified by RNS, and the four methods complement each other.