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体外反搏的发展概况及作用原理1953年 Kantrowitz 等首次提出升高舒张压以增加冠状动脉血流灌注的设想和实验。1962年 Moulopoulos 等设计了主动脉内气囊反搏的方法(简称内反搏)。人工结扎冠脉的动物实验证明内反搏能明显减少梗塞区,提高存活率。1967年开始临床应用,除用于急性心肌梗塞合并心源性休克及心脏直视手术后的低排血量综合征外,对一些顽固性心绞痛和梗塞前综合征的患者,也初步取得了较好的效果。
The development of extracorporeal counterpulsation and the principle of action In 1953, Kantrowitz et al for the first time raised the hypothesis of diastolic blood pressure to increase coronary perfusion and the idea. In 1962, Moulopoulos designed a method of intra-aortic balloon pump (EECP). Artificial ligation of the coronary artery animal experiments proved that internal counterpulsation can significantly reduce the infarct area, improve survival. Clinical application began in 1967, except for acute myocardial infarction complicated with cardiogenic shock and open heart surgery after low-volume syndrome, for some patients with refractory angina and pre-infarction syndrome, but also initially made more Good results.