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目的:探讨同步放化疗与单纯放疗治疗对中晚期食管癌的疗效和毒性反应。方法:将92例中晚期食管癌患者随机分为两组,同步放疗组行放射治疗+紫杉醇化疗,单纯放疗组仅行放射治疗。结果:同步放化疗组疗效高于单纯放疗组(P<0.05),毒性反应差异无统计学意义(P>0.05)。结论:同步放化疗治疗中晚期食管癌疗效明显优于单纯放疗,且毒性反应无明显差异,可耐受。
Objective: To investigate the efficacy and toxicity of concurrent chemoradiotherapy and radiotherapy alone in the treatment of advanced esophageal cancer. Methods: Ninety - two patients with advanced esophageal cancer were randomly divided into two groups. Radiotherapy + paclitaxel chemotherapy was used in the concurrent radiotherapy group, and only radiotherapy was given in the radiotherapy group. Results: The efficacy of concurrent chemoradiotherapy was higher than that of radiotherapy alone (P <0.05). There was no significant difference in toxicity (P> 0.05). Conclusions: The efficacy of concurrent chemoradiotherapy in the treatment of advanced esophageal cancer is better than that of radiotherapy alone, and no significant difference in toxicities can be tolerated.