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虽然已知皮质激素能影响血脂,但对长期接受这类药物的哮喘病人的高脂蛋白血症发生率则不了解。作者因发现接受皮质激素治疗2～2.5年的20例病人中,有4例由于心肌梗死在数月中相继死亡,故对一组长期接受本药治疗的哮喘病人进行了研究。研究对象为女性病人100名,年龄从29到75岁,均每日服强的松5～15毫克,连续4～13年。其中53人还每周注射ACTH凝胶40～120单位3～5年,
Although corticosteroids are known to affect blood lipids, they do not understand the incidence of hyperlipoproteinemia in long-term asthma patients receiving such drugs. The authors found that a group of asthmatic patients who had received this drug for a long time were found in 20 of 20 patients who received corticosteroid for 2 to 2.5 years and 4 patients died of myocardial infarction in several months. Study of 100 female patients, aged from 29 to 75 years old, were daily prednisone 5 to 15 mg for 4 to 13 years. 53 of them also injected ACTH gel 40 to 120 units 3 to 5 years per week,