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目的 了解结核病院人类免疫缺陷病毒(HIV)/结核分枝杆菌(MTB)双重感染发病情况及发现病例的临床表现、治疗对策。方法 对1995年2月～1999年2月3707例住院结核病患者常规检测HIV抗体。结果 3707例中HIV(+)4例,阳性率108‰。男3例,女1例。平均年龄295岁,占21～40岁年龄组的314‰。4例中血源性感染1例,异性间感染2例,另1例血源性、异性间感染难以确定。4例均可诊断为艾滋病(AIDS)。结论 对具有HIV感染危险因素的结核患者,特别是中青年,应常规进行HIV抗体检测,对HIV/MTB双重感染患者抗结核治疗时应特别注意药物副反应。在抗痨同时并用中西药抗AIDS治疗,结核病取得较好近期疗效。
Objective To understand the incidence of tuberculosis patients infected with human immunodeficiency virus (HIV) / Mycobacterium tuberculosis (MTB) and to find the clinical manifestations and treatment strategies. Methods From March 1995 to February 1999, 3707 inpatients with tuberculosis were routinely tested for HIV antibody. Results 3707 cases of HIV (+) 4 cases, the positive rate of 108 ‰. 3 males and 1 female. The average age is 295 years old, accounting for 314 ‰ of 21 ~ 40 age group. 1 case of blood-borne infection in 4 cases, 2 cases of heterosexual infection, the other 1 cases of blood-borne, heterosexual infection is difficult to determine. 4 cases were diagnosed as AIDS (AIDS). Conclusion HIV antibodies should be routinely tested in TB patients with risk factors for HIV infection, especially in middle-aged and young adults. Special attention should be paid to side effects of anti-TB drugs in patients with HIV / MTB dual infection. At the same time anti-tuberculosis and anti-AIDS treatment with traditional Chinese and Western medicine, tuberculosis achieved better recent efficacy.