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目的 观察选择性动脉插管化疗在晚期鼻咽癌综合治疗中的应用价值。方法 选择 70例局部晚期鼻咽癌初治患者 ,随机分成 2组各 3 5例 ,分别进行选择性动脉插管化疗 ( IACT)加放疗和全身化疗 ( SCT)加放疗 ,并采用配对的方法选择同期单纯放疗 ( RT)的鼻咽癌患者作为对照组 ,于放疗后对 3组的疗效进行比较。结果 IACT组完全缓解率及 2年局控率为65 .7%及 82 .9% ,SCT组为 5 4 .3 %和 77.1% ,RT组为 4 2 .9%及 5 1.4 %。结论 选择性动脉插管化疗加放疗治疗晚期鼻咽癌 ,短期疗效显著 ,副作用轻。
Objective To observe the value of selective arterial intubation chemotherapy in the comprehensive treatment of advanced nasopharyngeal carcinoma. Methods Seventy patients with locally advanced nasopharyngeal carcinoma were randomly divided into 2 groups and 35 cases. They were treated with selective arterial intubation chemotherapy (IACT) plus radiotherapy and systemic chemotherapy (SCT) plus radiotherapy, and they were selected by pairing. Patients with nasopharyngeal carcinoma who received radiotherapy alone (RT) during the same period served as a control group and compared the efficacy of the three groups after radiotherapy. Results In the IACT group, the complete remission rate and the 2-year control rate were 65.7% and 82.9%. The SCT group was 54.7% and 77.1%. The RT group was 42.9% and 5.14%. Conclusion Selective arterial intubation chemotherapy combined with radiotherapy for advanced nasopharyngeal carcinoma has short-term efficacy and mild side effects.