A new virginae butanolide from Streptomyces sp.

• 作 者: Xiang LI Yi Nan ZHENG Wen Han
• 机 构: Department of Chinese Medicine,State Key Laboratory of Natural and Biomimetic Drugs,Hans-Kn(o)ll-Ins
• 出 处: 中国化学快报（英文版）
• 发表日期: 2004年期
• 关键词: Virginaebutanolide C virginaebutanolide F Streptomyces sp
• 基金项目: This work is a part of a collaboration between the Hans-Kn(o)ll-Institute for Natural Product Research（HKI）;the National Research Laboratory of Natural and Biomimetic Drugs, Peking University（PKU）;was

A novel butanolide, named virginaebutanolide F (1), was isolated from the lyophilized culture broth of Streptomyces sp., along with a known compound virginaebutanolide C (2). Their structures including the stereochemistry were elucidated on the basis of extensive 1D and 2D NMR as well as HRESI-MS and CD spectroscopic analysis.