卵车前和欧车前中的酚性成分

• 作 者: 张贵峰
• 出 处: 国外医学(中医中药分册)
• 发表日期: 2003年02期
• 关键词: 酚性成分 正丁醇萃取 甲醇提取 硅胶柱层析 Plantago 减压浓缩 芹菜糖 萃取液 梯度洗脱 分离纯化

车前科植物欧车前(Plantago psyllium)的干燥成熟种子用于治疗便秘,卵车前(P.ovata)也有相同的作用。Nishibe S将卵车前种子粉碎后,取500g用热甲醇提取,提取液在40℃时减压浓缩至1/5,加水过滤,滤液依次以乙醚、乙酸乙酯和正丁醇萃取,各萃取液在40℃时减压回收溶剂至干。乙酸乙酯部分(1.2g)进行硅胶柱层析,5％～20％乙醇-氯仿梯

The dried ripe seeds of Plantago psyllium are used to treat constipation, and P.ovata has the same effect. Nishibe S crushed the eggs before the vehicle seeds, take 500g with hot methanol extraction, the extract was concentrated under reduced pressure at 40 °C to 1/5, add water filtration, the filtrate was sequentially extracted with ethyl ether, ethyl acetate and n-butanol, each extract The solvent was recovered under reduced pressure at 40 °C until dryness. The ethyl acetate fraction (1.2 g) was subjected to silica gel column chromatography, 5% to 20% ethanol-chloroform ladder