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观察精神分裂症患者血浆对小鼠行为效应及脑组织形态学改变。方法注射精神分裂症患者血浆组小鼠和注射正常人血浆组各１０只，注射生理盐水组１０只做为对照组。结果正常人血奖组与生理盐水对照组小鼠行为及脑组织形态学无明显变化，精神分裂症血浆组行为兴奋性增高，脑组织神经胶质细胞增生，形成胶质细胞结节。结论提示精神分裂症患者血浆中存在某些生物学致病物质，感染或自身免疫可能参与某些精神分裂症患者发病。
To observe the behavioral effects of mice with schizophrenia on the behavior of mice and brain morphological changes. Methods 10 schizophrenic patients with plasma and 10 normal saline injected and 10 normal saline as control. Results There was no significant change in behavior and brain histomorphology between the normal group and the saline control group. The behavioral excitability of the schizophrenic plasma group was increased, and glial cells proliferated in the brain tissue to form glial cell nodules. The conclusions suggest that some biological pathogens exist in the plasma of patients with schizophrenia, and infection or autoimmunity may be involved in the pathogenesis of some schizophrenia patients.