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目的:了解乌鲁木齐市中医医院药品不良反应(ADR)的发生特点及引发ADR的相关因素,为临床合理用药提供参考。方法对乌鲁木齐市中医医院2011年收集的96例报告进行回顾性分析。结果96例ADR报告中,以静脉滴注给药引发的ADR最多,占总例数的94.79%(91例);其次是抗菌药物引起的ADR,占总例数的69.97%(67例);ADR表现以皮肤及附件损伤最为常见,占总例数的48.96%(47例)。结论给药途径、药物种类等因素均会影响ADR的发生,临床应重视药品不良反应的报告及检测,减少注射剂的使用,合理使用抗菌药物,以减少或避免ADR的发生。
Objective: To understand the characteristics of adverse drug reaction (ADR) in Urumqi Hospital of Chinese Medicine and the related factors that cause ADR, so as to provide a reference for clinical rational drug use. Methods A retrospective analysis was performed on 96 cases collected by Urumqi Hospital of Traditional Chinese Medicine in 2011. Results The ADRs caused by intravenous drip in 96 cases of ADR cases were the highest, accounting for 94.79% (91 cases) of the total cases, followed by antibiotics - induced ADR (69.97%, 67 cases) ADR showed the most common skin and accessory injury, accounting for 48.96% (47 cases) of the total number of cases. Conclusions The route of administration, the type of drug and other factors will affect the occurrence of ADR. Clinical reports should focus on adverse drug reactions and testing, reduce the use of injections and use antimicrobial agents rationally to reduce or avoid the occurrence of ADR.