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[目的]观察舒血宁联合西药治疗瘀血阻络型急性脑梗塞疗效。[方法]使用随机平行对照方法,将100例门诊及住院患者按病志号抽签法简单随机分为两组。溶栓治疗、抗凝、降纤、血液稀释、脑保护剂钙离子拮抗剂等治疗。对照组50例120mg川芎嗪+250m L 0.9g氯化钠,1次/d。治疗组50例20m L舒血宁+250m L 0.9g氯化钠,1次/d。连续治疗7d为1疗程。观测临床症状、全血黏度低切、全血黏度高切、血浆黏度、功能缺损评分、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组痊愈30例,显效12例,有效4例,无效4例,总有效率92.00%。对照组痊愈21例,显效10例,有效7例,无效12例,总有效率76.00%。治疗组疗效优于对照组(P<0.05)。血液流变指标两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。神经功能缺损评分两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]舒血宁联合西药治疗瘀血阻络型急性脑梗塞疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Shuxuening combined with western medicine on blood stasis obstruction type acute cerebral infarction. [Methods] Using randomized parallel control method, 100 cases of outpatients and inpatients were randomly divided into two groups randomly according to the method of lot drawing. Thrombolytic therapy, anticoagulation, fibrinolysis, hemodilution, brain protective agents such as calcium antagonists. Control group, 50 cases of 120mg Ligustrazine + 250ml L 0.9g sodium chloride, 1 times / d. The treatment group 50 cases of 20m L Shuxuening + 250m L 0.9g sodium chloride, 1 time / d. Continuous treatment 7d for a course of treatment. Observation of clinical symptoms, low blood viscosity of whole blood, high blood viscosity of whole blood, plasma viscosity, functional impairment score, adverse reactions. Continuous treatment of 2 courses to determine the efficacy. [Result] The treatment group cured 30 cases, 12 cases markedly effective, 4 cases effective, 4 cases ineffective, the total effective rate was 92.00%. The control group cured 21 cases, markedly effective in 10 cases, effective in 7 cases, ineffective in 12 cases, the total effective rate was 76.00%. The treatment group was better than the control group (P <0.05). The indexes of hemorheology were improved in both groups (P <0.05), and the improvement in the treatment group was better than that in the control group (P <0.05). Neurological deficit scores were improved in both groups (P <0.05), and the treatment group improved better than the control group (P <0.05). [Conclusion] Shuxuening combined with western medicine is effective in treating blood stasis obstruction type acute cerebral infarction without serious adverse reactions and is worth promoting.