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通过对３２例喉癌患者围手术期血清ｓＩＬ－２Ｒ与急性期蛋白（α１—ＡＴ、α１—ＡＧ、ＨＰ）的检测，发现喉癌患者围手术期血清ｓＩＬ－２Ｒ与急性期蛋白明显高于正常人，且二者有正相关性（Ｐ＜０．０１）。在喉癌患者中，声门上型和混合型喉癌的上述指标水平高于声门型喉癌（Ｐ＜０．０１），临床Ⅲ、Ⅳ期喉癌患者血清中ｓＩＬ－２Ｒ与急性期蛋白水平高于Ⅰ、Ⅱ期患者（Ｐ＜０．０５及Ｐ＜０．０１），手术后短期内ｓＩＬ－２Ｒ水平升高。因此，ｓＩＬ－２Ｒ与急性期蛋白联合检测，对喉癌的临床分型、分期、疗效评价及预后监测均具有指导意义，且具有简便、快速、无创伤等优点，可广泛应用于临床。
Through perioperative serum sIL-2R and acute phase protein (α1-AT, α1-AG, HP) in 32 patients with laryngeal cancer, the serum sIL-2R and acute phase protein in patients with laryngeal cancer were significantly higher than those in acute phase There was a positive correlation between them (P <0.01). In laryngeal cancer patients, supraglottic and mixed laryngeal cancer above indicators than glottic laryngeal cancer (P <0.01), clinical stage Ⅲ, Ⅳ laryngeal cancer serum sIL-2R and acute phase The level of sIL-2R was higher in patients with stage Ⅰ and Ⅱ (P <0.05 and P <0.01). Therefore, the combined detection of sIL-2R and acute phase protein has guiding significance for the clinical classification, staging, curative effect evaluation and prognosis monitoring of laryngeal carcinoma, and has the advantages of simplicity, rapidity, noninvasiveness and the like and can be widely used in clinic.