论文部分内容阅读
目的了解血压正常男、女年轻人群(16～30岁)动脉功能参数:脉搏曲线分析指数[大动脉弹性指数(C1)和小动脉弹性指数(C2)]、颈股动脉脉搏波传导速度(cfPWV)和颈桡动脉脉搏波传导速度(crPWV)及其他生理指标之间的关系。方法入选血压正常志愿者共270例,年龄16～30岁,男性112例,女性158例,调查受试者基本资料,并采用CVProfilor DO-2020型动脉功能检测仪和脉搏波传导速度(PWV)测定仪分别测量C1、C2及cfPWV、crPWV。对动脉弹性指标和心血管疾病相关生理指标的关系进行分析。结果男性C1与身高、体质量呈正相关,与收缩压、平均动脉压(MAP)、脉压和心率呈负相关,其中与脉压相关性最大(r=-0.532,P<0.01);C2与收缩压、舒张压、MAP和心率呈负相关,其中与收缩压相关性最大(r=-0.319,P<0.01);cfPWV与舒张压和年龄呈正相关;crPWV与年龄、舒张压、身高和体质量呈正相关。女性相关关系与男性相似,其中C1和脉压相关性最大(r=-0.514,P<0.01),C2与心率的相关性最大(r=-0.552,P<0.01);cfPWV、crPWV均与舒张压、MAP、收缩压呈正相关,与舒张压相关性最大。结论血压、心率和肥胖相关指标是影响年轻人C1、C2的重要因素,舒张压对PWV产生影响。
Objective To understand the arterial function parameters in normal normotensive men and young women (16 ~ 30 years old): pulse wave analysis index (arterial elasticity index (C1) and arterial elasticity index (C2)], carotid artery pulse wave velocity (cfPWV) And carotid artery pulse wave velocity (crPWV) and other physiological indicators of the relationship. METHODS: A total of 270 volunteers with normal blood pressure were enrolled in this study. They were aged from 16 to 30 years old, including 112 males and 158 females. The subjects were surveyed. CVProfilor DO-2020 arterial function detector and pulse wave velocity (PWV) The analyzer measured C1, C2 and cfPWV, crPWV respectively. The relationship between arterial elasticity index and cardiovascular related physiological index was analyzed. Results Male C1 was positively correlated with height and weight, and negatively correlated with systolic pressure, mean arterial pressure (MAP), pulse pressure and heart rate (P <0.01). The correlation between C2 and Systolic blood pressure, diastolic blood pressure, MAP and heart rate were negatively correlated with the systolic pressure (r = -0.319, P <0.01); cfPWV and diastolic blood pressure and age were positively correlated; crPWV and age, diastolic blood pressure, height and body Quality is positively correlated. The correlation between C1 and pulse pressure was the highest (r = -0.514, P <0.01), and the correlation between C2 and heart rate was the highest (r = -0.552, P <0.01); cfPWV and crPWV were both related to diastolic Pressure, MAP, systolic blood pressure were positively correlated, and diastolic blood pressure was the highest. Conclusion The related indexes of blood pressure, heart rate and obesity are important factors that affect young people C1 and C2, and diastolic blood pressure has an impact on PWV.