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狼疮性肾炎 (LN)是典型的自身免疫性疾病 ,其主要免疫学特征是多克隆淋巴细胞的活化、自身抗体产生和炎症细胞因子的释放增加。尽管自身免疫性疾病的确切原因并不清楚 ,近几年来大多数研究者都在探求一种特异性自身抗体在LN致病过程中所起的作用。近年来已从特异性自身抗体
Lupus nephritis (LN) is a classic autoimmune disease whose major immunological hallmarks are the activation of polyclonal lymphocytes, the production of autoantibodies and the increased release of inflammatory cytokines. Although the exact cause of autoimmune diseases is not clear, most researchers in recent years are exploring the role of specific autoantibodies in LN pathogenesis. In recent years has been from the specific autoantibodies