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钙拮抗剂自60年代提出后,主要用于心血管疾病。1976年以来实验及临床资料均证实此类药物对神经系统疾病有治疗作用。尼莫地平(Nimodipine,N D)为一选择性扩张脑血管作用较强的有机钙拮抗剂,被认为是治疗脑血管痉挛和脑缺血疾患很有希望的药物。西德于1985年5月投入市场。国内现已合成生产。
Calcium antagonists have been proposed since the 1960s and are mainly used for cardiovascular diseases. Since 1976, experimental and clinical data have confirmed that these drugs have a therapeutic effect on nervous system diseases. Nimodipine (N D) is an organic calcium antagonist with a selective effect of selectively expanding cerebral blood vessels and is considered as a promising drug for the treatment of cerebral vasospasm and cerebral ischemia. West Germany in May 1985 into the market. Domestic synthesis is now production.