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目的：探讨慢性心力衰竭合并肾功能不全患者的临床特征。方法回顾性分析374例以慢性心力衰竭为第一诊断的住院患者病例资料，根据我国改良 MDRD 方程估算患者的肾小球滤过率，据此分为正常组106例、轻度肾功能不全组129例、肾功不全组139例，比较不同肾功能状态患者的临床特征、预后情况。结果随着年龄的增长，慢性心衰患者的肾功能出现恶化趋势，肾功能不全者平均住院日明显延长。肾功能不全组血红细胞、血红蛋白明显低于轻度肾功能不全组及正常组（P ＜0．05），并且钾离子浓度、血磷浓度、血尿酸、血尿素氮、B 型利钠肽（BNP）、肌钙蛋白 T （TNT）阳性率、2年内死亡人数明显高于肾功能轻度不全组及正常组（P ＜0．05）。年龄、红细胞、血红蛋白、肌酐、尿素氮、TNT 情况为影响患者2年内死亡的相关危险因素。结论慢性心力衰竭合并肾功能不全发病率高，平均年龄大，住院天数相对较长，2年内死亡率增加。患者红细胞、血红蛋白水平相对较低，血钾浓度、血磷浓度、血尿素氮、血尿酸、BNP、TNT 水平相对较高。“,”Objective To investigate the clinical characteristics of chronic heart failure complicated with renal insufficiency.Methods A retrospective analysis of 374 patients with chronic heart failure as the first diagnosis of hospitalized patients,according to the modified MDRD equation of the patients with esti-mated glomerular filtration rate,all the patients were divided into control group (n =106),mild renal in-sufficiency group (n =129)and renal insufficiency group (n =139).The clinical characteristics and prognosis were compared among groups.Results Renal function of chronic heart failure patients deterio-rated with age,and the average hospital stay was significantly prolonged for renal insufficiency group. The red blood cells and the hemoglobin of the renal insufficiency group were significantly lower than the mild renal insufficiency group and normal group (P <0.05).For renal insufficiency group,the potassium concentration,serum phosphorus concentration,serum uric acid concentration,urea nitrogen concentra-tion,brain natriuretic peptide (BNP)and troponin T (TNT)positive rate,and the dead cases of renal inefficiency in two years were higher than mild renal insufficiency group and normal group (P <0.05). Age,red blood cell,hemoglobin,creatinine,urea nitrogen concentration and TNT were the risk factors of death in two years.Conclusion Chronic heart failure complicated with renal insufficiency has a highincidence in aged people,and the hospital stay is relatively long.The mortality increases in two years. The patients with chronic heart failure combined renal insufficiency has low level of red blood cells and hemoglobin,as well as the high level of serum potassium concentration,blood phosphorus concentration, blood urea nitrogen,blood uric acid,brain natriuretic peptide and troponin T.