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目的:观察中西医结合治疗低出生体重儿黄疸的临床疗效。方法:选取86例黄疸低出生体重儿为研究对象,随机分为对照组和研究组各43例。对照组给予吸氧、抗感染、纠正酸中毒、苯巴比妥驱黄及蓝光照射等治疗,研究组在对照组治疗基础上给予茵栀黄口服液合双歧杆菌三联活菌散治疗。治疗后比较2组临床疗效及黄疸消退时间、住院时间,观察2组治疗前后血清总胆红素水平的变化。结果:对照组治愈率37.21%,研究组治愈率62.79%,2组比较,差异有统计学意义(P<0.05)。治疗后,研究组黄疸消退时间及住院时间均短于对照组,差异均有统计学意义(P<0.05)。治疗3天后,2组血清总胆红素水平均较治疗前降低(P<0.05),研究组的血清总胆红素水平低于对照组(P<0.05)。治疗5天后,2组血清总胆红素水平均较治疗前和治疗3天后降低(P<0.05),研究组的血清总胆红素水平低于对照组(P<0.05)。结论:中西医结合治疗低出生体重儿黄疸,效果显著,能有效促进黄疸消退,缩短住院时间,降低血清总胆红素水平。
Objective: To observe the clinical efficacy of integrated traditional Chinese and western medicine in treating jaundice in low birth weight infants. Methods: 86 cases of jaundice and low birth weight children were selected as study object and randomly divided into control group and study group, 43 cases each. The control group was given oxygen, anti-infection, correct acidosis, phenobarbital yellow and blue light irradiation and other treatment groups in the control group on the basis of treatment given Yinzhihuang oral liquid Bifidobacterium triple live bacterial powder treatment. After treatment, the clinical efficacy, jaundice extinction time and hospital stay were compared between the two groups before and after treatment to observe the changes of serum total bilirubin levels. Results: The cure rate of the control group was 37.21%, the cure rate of the study group was 62.79%. There was significant difference between the two groups (P <0.05). After treatment, the study group jaundice extinction time and hospital stay were shorter than the control group, the difference was statistically significant (P <0.05). After 3 days of treatment, the total serum bilirubin levels in both groups were significantly lower than those before treatment (P <0.05). The serum total bilirubin level in the study group was lower than that in the control group (P <0.05). After 5 days of treatment, the serum total bilirubin levels in both groups were significantly lower than those before and 3 days after treatment (P <0.05). The serum total bilirubin level in the study group was lower than that in the control group (P <0.05). Conclusion: Integrative medicine treatment of low birth weight children jaundice, the effect is significant, can effectively promote the jaundice subsided, shorten the hospital stay, reduce the serum total bilirubin level.