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目的探讨并比较额叶癫痫治疗方法及效果。方法采用术中脑皮层电极（ＥＣｏＧ）探测定位，然后根据具体情况选用或联用胼胝体切开术（ＣＣＳ），局部痫灶切除及多软膜下横纤维切断（ＭＳＴ）。对双额叶痫灶或ＥＣｏＧ发现为双额叶同步放电者，应先完成胼胝体切开术，当痫灶位于额叶的主要功能区包括运动，语言区时，应采用ＭＳＴ，ＭＳＴ也可应用于一侧半球广泛弥散性痫灶的患者。４０例额叶癫痫患者经上述２～３种方法联合治疗后，疗效满意。结果术后一个月内，绝大多数患者痫性发作消失，无严重并发症，无手术死亡。随访６个月至３年，平均２．５年。发作消失的１９例（４８％）；发作每年少于３次或无真性发作１１例（２８％）；发作明显减轻６例（１５％）；同术前无改善４例（１０％），有效率９０％。结论在皮层电极指导下采用痫灶切除并联合应用胼胝体切开或多软膜下横切是治疗额叶癫痫的有效方法。
Objective To explore and compare the treatment of frontal lobe epilepsy and its effects. Methods The intraoperative cortical electrodes (ECoG) were used to detect the location. According to the specific situation, we selected or combined with corpus callosum incision (CCS), partial epileptogenic focus and multi-subdural transection (MST). For double-frontal eclampsia or ECoG found double-frontal concurrent discharge should be completed before the corpus callosum incision, when the main functional areas of the frontal lobe of the epileptogenic focus, including movement, language area, should be used MST, MST can also be applied Patients with extensive disseminated epilepsy on one hemisphere. 40 cases of frontal lobe epilepsy patients by the above 2 ~ 3 methods combined treatment, the effect is satisfactory. Results Within one month after operation, the majority of patients had seizures disappeared without serious complications and no operative death. Follow-up 6 months to 3 years, an average of 2.5 years. Nine episodes (48%) with episodes disappeared; seizures less than three episodes per year or 11 episodes of unnotic seizures (28%); six episodes (15%) markedly reduced seizures; four (10% Efficiency 90%. Conclusion Under the guidance of cortical electrodes, epileptogenic resection and combined application of corpus callosum or multiple subdural transection are effective methods for the treatment of frontal lobe epilepsy.