论文部分内容阅读
目的了解长春地区婴幼儿腹泻人类杯状病毒(Human calicivirus,HuCV)感染的流行情况。方法用RT-PCR法检测腹泻患儿粪便标本中HuCV。结果长春地区婴幼儿腹泻HuCV检出率为18%。HuCV腹泻以2岁以下儿童为主(占96%)。流行高峰季节为11月至次年3月。选择19株HuCV进行分子鉴定,16株属GII-4群,2株属GII-3群,另一株属GI-2群,表明GII-4群为本地区优势株。5岁以下儿童中HuCV腹泻在年龄和季节分布上都与轮状病毒腹泻很相似。结论长春地区婴幼儿杯状病毒感染的流行病学调查为我国病毒感染性腹泻的预防和控制提供科学依据。
Objective To understand the epidemic situation of human calicivirus (HuCV) infection in infantile diarrhea in Changchun area. Methods HuCV was detected by RT-PCR in stool samples from children with diarrhea. Results The detection rate of HuCV in infants and infants in Changchun was 18%. HuCV diarrhea is dominated by children under 2 years old (96%). The peak season is from November to March. 19 strains of HuCV were selected for molecular identification. 16 strains belong to GII-4 group, 2 strains belong to GII-3 group and the other belongs to GI-2 group, indicating that GII-4 group is dominant in this region. HuCV diarrhea in children under 5 years old is very similar to rotavirus diarrhea in age and season distribution. Conclusions Epidemiological investigation of goblet virus infection in Changchun provides a scientific basis for the prevention and control of viral infectious diarrhea in our country.