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目的 加强对宫颈微腺体增生的认识。方法 报告 5例宫颈微腺体增生 ,其中包括 2例不典型宫颈微腺体增生 ,并进行了特殊染色及免疫组化标记。结果 患者平均年龄 44岁 ,其中 1例有口服避孕药史。通过分析本文概括了该病变典型与不典型的组织学特征 :密集集合的大小不等的腺体、部分区呈网状或实性的图象、间质或腺腔中炎细胞的浸润、可出现上皮的多形性及核深染但无核分裂或核分裂偶见 (≤ 1 /1 0HPF) ;强调了可能与恶性肿瘤相混淆的不典型宫颈微腺体增生的诊断与鉴别诊断要点 ;分析了特殊染色PAS、AlcianBlue及免疫酶标CEA单抗、P5 3、Ki 6 7在诊断与鉴别诊断中的意义。结论 宫颈微腺体增生是一种完全良性病变 ,认识该病变对外检工作中避免误诊具有重要意义
Objective To strengthen the understanding of cervical microglandular hyperplasia. Methods Five cases of cervical microglandular hyperplasia were reported, including 2 cases of atypical cervical microglandular hyperplasia and special staining and immunohistochemical staining. Results The average age of patients was 44 years, of which 1 case had history of oral contraceptives. By analyzing this paper, we summarize the typical and atypical histological features of the lesion: densely gathered glands of varying sizes, some areas of reticular or solid images, infiltration of inflammatory cells in stroma or glandular cavity, Occurrence of epithelial pleomorphism and nuclear staining but no mitotic or mitotic occasional (≤ 1 / 100HPF); highlighted may be confused with malignant tumors of atypical cervical microglial hyperplasia diagnosis and differential diagnosis points; analysis of Special staining PAS, AlcianBlue and CEA monoclonal antibody, P5 3, Ki 6 7 in the diagnosis and differential diagnosis. Conclusions Cervical microglandular hyperplasia is a complete benign lesion. It is of great importance to recognize the lesion to avoid misdiagnosis during the external examination