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采取药物使用处方分析,临床医生的评价,过量用药中毒急诊室调查和随访调查等多种方法对氨酚待因片上市后的不良反应,尤其是它在人群中产生依赖性或药物滥用的可能性进行了流行学考察与评价,并继续考察了本品的疗效。结果表明:(1)本品具有较好的镇痛作用,有效率达81.3%,其疗效涉及到多种疼痛;(2)无论对临床医生的调查还是随访调查,均未发现本品所致严重不良反应病例,氨酚待因片具有头晕、出汗、倦乏等轻度副作用,但发生率较低(0.8%);(3)药物依赖性和药物滥用流行学研究未发现氨酚待因片成瘾病例和在人群中滥用的倾向;(4)药物使用处方分析表明医院每天氨酚待因片的实际消耗量较低,只有24.24±14.81(X±SD)个DDD,绝大多数(94.6%) 的处方用药指数(DUT)都小于1.0,说明医生对开写本品相当慎重,用药基本合理。
Adopting the prescription analysis of drug use, the evaluation of clinicians, the emergency room investigation and follow-up investigation of overdose poisoning and so on, the adverse reaction to paracetamol to be listed on the market, especially its dependence on drug abuse or possible drug abuse Sex conducted a survey and evaluation of epidemiology, and continue to examine the efficacy of this product. The results showed that: (1) This product has a good analgesic effect, the effective rate of 81.3%, the effect involves a variety of pain; (2) regardless of the clinician survey or follow-up survey, did not find this product caused by Severe adverse reactions, paracetamol tablets have dizziness, sweating, fatigue and other minor side effects, but the incidence was low (0.8%); (3) drug dependence and drug abuse epidemiological studies found no Paracetamol to be (4) Prescription analysis of drug use indicated that the actual consumption of paracetamol in the hospital was relatively low at 24.24 ± 14.81 (X ± SD) DDD per day, the vast majority (94.6%) of the prescription medication index (DUT) are less than 1.0, indicating that the doctor to write this product is very cautious, medication is reasonable.