论文部分内容阅读
目的:了解武汉市江岸区人群出生缺陷发生状况,为制定干预措施提出依据。方法:利用武汉市产科质量监测系统,采用人群监测方法收集出生缺陷资料,运用SPSS 17.0软件进行数据分析。结果:2010~2012年3年共调查围产儿19782例,发生出生缺陷人数136例,出生缺陷发生率6.87‰,年度比较差异有统计学意义(P<0.01)。其中,男性73例,女性61例,性别不详2例,男女出生缺陷发生率比较无统计学意义(P>0.05),城镇126例、农村10例;出生缺陷患病率前3位分别为多指多趾和并指并趾、外耳其他畸形;出生缺陷转归情况活产66.18%、死胎30.88%,7天内死亡2.94%;出生缺陷诊断依据临床65.45%、产前超声33.09%、染色体0.74%、其他0.74%;出生缺陷诊断时间产前为33.82%、产后7天为66.18%;诊断为出生缺陷后治疗性引产34.00%、未进行治疗性引产64.71%。结论:男性出生缺陷发生率高于女性,城镇明显高于农村;要进一步提高婚前检查,加强产前健康管理,积极开展产前筛查工作,加强优生优育宣传。
Objective: To understand the occurrence of birth defects in Jiang’an District of Wuhan City and to provide the basis for the formulation of intervention measures. Methods: Wuhan obstetrics quality monitoring system, the use of population monitoring methods to collect birth defects data, the use of SPSS 17.0 software for data analysis. Results: A total of 2,982 perinatal infants were investigated during the three years from 2010 to 2012, with 136 birth defects and a birth defect rate of 6.87 ‰. The annual difference was statistically significant (P <0.01). Among them, there were 73 males and 61 females with 2 males and 2 males. The incidence of birth defects in men and women was not statistically significant (P> 0.05), 126 in urban areas and 10 in rural areas. The top 3 prevalences of birth defects were respectively Refers to more than and refers to the toe and other deformities of the outer ear; birth defects go to the situation of live birth 66.18%, stillbirth 30.88%, 2.94% within 7 days of death; diagnosis of birth defects based on clinical 65.45%, 33.09% prenatal ultrasound, chromosome 0.74% , While the others were 0.74%. The time of diagnosis of birth defects was 33.82% before giving birth and 66.18% after giving birth for 7 days. After the birth defect was diagnosed, 34.00% of the patients were treated with induced abortion and 64.71% without using induced labor. Conclusions: The incidence of male birth defects is higher than that of women, and the urban area is obviously higher than that of rural areas. To further improve premarital health examination, strengthen prenatal health management, actively carry out prenatal screening and strengthen prenatal and postnatal care publicity.