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目的探讨奥美拉唑、克拉霉素、替硝唑三联在胃溃疡治疗中的效果,为其治疗方式的选择提供依据。方法选取2009年1月至2010年12月于偃师市人民医院进行治疗的130例胃溃疡患者为研究对象,将其随机分为对照组(西咪替丁、阿莫西林、甲硝唑)65例和治疗组(奥美拉唑、克拉霉素、替硝唑组)65例,将两组患者的幽门螺杆菌(HP)根除率和临床治疗效果进行比较分析。结果观察组的治疗总有效率和HP根除率明显高于对照组(P<0.05)。结论在胃溃疡的治疗中,采用奥美拉唑、克拉霉素、替硝唑三联的治疗方案效果佳。
Objective To investigate the effect of omeprazole, clarithromycin and tinidazole triple therapy in the treatment of gastric ulcer, and provide the basis for the choice of treatment. Methods A total of 130 gastric ulcer patients treated in Yanshi People’s Hospital from January 2009 to December 2010 were selected and divided into control group (cimetidine, amoxicillin, metronidazole) 65 cases and treatment group (omeprazole, clarithromycin, tinidazole group) 65 cases, the two groups of patients with Helicobacter pylori (HP) eradication rate and clinical treatment were compared. Results The total effective rate and HP eradication rate in the observation group were significantly higher than those in the control group (P <0.05). Conclusion In the treatment of gastric ulcer, the treatment with omeprazole, clarithromycin and tinidazole is effective.