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We report a microstructure-fibre-based parametric amplification experiment in telecom band with ultra-high gain slope. A peak on-off gain of 52.3 dB is achieved using 25 m high nonlinear microstructure fibre (MF) and only 5.3 W pump power. The parametric gain slope is up to 580dBW-1 km-1. From the experimental data, the linear coefficient of the MF is estimated to be about 66. 7 W-1 km-1. The experiment shows the great potential of MFs in practical fibre parametric amplifiers.