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本文报道冈比亚某地在进行为期5年的化学预防研究之前,该地区恶性疟原虫对乙胺嘧啶(PYR),及其与氨苯酚(DP)的复方迈咯平(MLP)和氯喹(CQ)的敏感性。实验观察对象为1~7岁农村儿童,测腋温后,指端采血涂制厚薄血膜,并采血1.0ml放入含肝素的RPMI1640完全培养液(RPS,含RPMI 1640 10.4g/L,HEPES 5.9g/L,NaHCO_32g/L,PABA 1μg/L,庆大霉素12.5mg/L和10%小牛血清)内,在常温(25~38℃)下避光保存,6小时内带回实验室置37℃下待检。体内法药效测定分两组:体温正常(37.5℃组,按编号顺序分别给予顿服单
This article reports that Pyrrhotida pallidum (Pf) and its combination with paracetamol (DP) and pyrimethamine (CQ) in the area of Gambia, prior to the 5-year study of chemical prophylaxis, Sensitivity. Experimental observation was performed on rural children aged from 1 to 7 years. After measurement of axillary temperature, thick blood films were drawn on the fingertip blood and 1.0 ml of blood was collected into RPMI1640 complete medium containing heparin (RPS, RPMI 1640 10.4 g / L, HEPES 5.9 g / L, NaHCO_32 g / L, PABA 1 μg / L, gentamicin 12.5 mg / L and 10% calf serum) at room temperature Room to be seized at 37 ℃. Pharmacodynamic determination of the body law divided into two groups: normal body temperature (37.5 ℃ group, according to the order of numbers given Dayton single