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目的探讨慢性正己烷中毒对中枢神经系统的损害。方法对28例临床诊断为正己烷中毒的患者进行脑电图检测,并随机选取30例健康成年人作为对照组。结果正己烷中毒组有24例患者存在不同程度脑电图异常,占检测总数的85.7%,正常对照组中2例轻度异常(6.7%),2组比较,差异有统计学意义(P<0.01)。结论正己烷不但可以导致周围神经系统损害,亦可能导致中枢神经系统功能损害。
Objective To investigate the chronic n-hexane poisoning of the central nervous system damage. Methods EEG was performed in 28 patients with n-hexane poisoning and 30 healthy adults were randomly selected as the control group. Results Twenty-four patients in n-hexane poisoning group had different degrees of EEG abnormalities, accounting for 85.7% of the total number of patients in the n-hexane poisoning group and 2 mild abnormalities (6.7%) in the normal control group. There was significant difference between the two groups (P < 0.01). Conclusion n-Hexane not only can cause peripheral nervous system damage, may also lead to central nervous system dysfunction.