论文部分内容阅读
为探讨肝动脉插管免疫化疗栓塞术（ Ｔ Ａ Ｉ Ｃ Ｅ） 与化疗栓塞术（ Ｔ Ａ Ｃ Ｅ） 在治疗中晚期肝癌的疗效与毒副作用。随机将病人分成两组，治疗组采用 Ｔ Ａ Ｉ Ｃ Ｅ 法共２５ 例，对照组２１ 例，采用 Ｔ Ａ Ｃ Ｅ 法。均按照ｓｅｌｄｉｎｇｅｒ 方法，穿刺股动脉，放入肝动脉导管到肝固有动脉以上，对照组灌入５ Ｆ Ｕ、 Ａ Ｄ Ｍ、 Ｍ Ｍ Ｃ 化疗药物，治疗组在对照组用药基础上加入免疫药物白细胞介素Ⅱ。按照１９９３ 年卫生部制订《中药治疗原发性肝癌的临床研究指导原则》癌灶客观疗效判定标准。治疗组显效率５６ ％ ，总有效率８８ ％ ；对照组显效率１９ ％ ，总有效率６１９ ％ ，二者的显效率及总有效率经χ２ 检验差异有显著性（ Ｐ＜ ０ ．０５） 。两组毒副作用统计学处理无显著差异，说明肝动脉插管免疫化疗栓塞术治疗中晚期原发性肝癌比单纯化疗栓塞术疗效显著。
To investigate the efficacy and toxic side effects of hepatic arterial intubation immunochemotherapy embolization (TAIC) and chemoembolization (TAC E) in the treatment of advanced liver cancer. The patients were randomly divided into two groups. The treatment group used T A I C E method for a total of 25 cases and the control group for 21 cases, using the T A C E method. According to the seldinger method, the femoral artery was punctured, and the hepatic artery catheter was placed into the superior hepatic artery. The control group was infused with 5 F U, A D M, M M C chemotherapeutic drugs. The treatment group was added with immunological drugs on the basis of the drug in the control group. Interleukin II. According to the Ministry of Health in 1993, the Guiding Principles for Clinical Research of Chinese Medicine for Primary Hepatocellular Carcinoma were established to determine the objective therapeutic efficacy of cancer stoves. The effective rate of the treatment group was 56% and the total effective rate was 88%. The control group had significant efficiency of 19% and the total effective rate of 61.9%. The significant efficiency and total effective rate of the two groups were significantly different by the χ2 test (P<0.05). ). There was no significant difference between the two groups in statistical treatment of toxic and side effects, indicating that hepatic artery catheterization and immunotherapy chemoembolization for the treatment of advanced primary liver cancer is more effective than chemotherapy embolization alone.