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目的:探讨左侧卧位I-scope气管插管用于内镜黏膜下剥离术(ESD)能否优化术前麻醉时间。方法:2018年3—12月于首都医科大学附属北京友谊医院拟行ESD的150例早期胃食管癌患者纳入研究，根据SPSS 20.0随机数字分为3组，每组50例。SL组患者左侧卧位，使用I-scope气管插管；SS组患者平卧位，使用I-scope气管插管；MS组患者平卧位，Macintosh喉镜直接气管插管。主要观察术前非必需麻醉时间(气管插管成功后至内镜手术开始的间隔时间)、气管插管成功的插管次数、相关并发症等并行统计分析。结果:SL组的术前非必需麻醉时间为(8.55±2.16)min，SS组为(10.44±2.43)min，MS组为(10.56±3.20)min，3组间差异有统计学意义(n F＝9.08，n P<0.001)，SL组明显少于SS组(n P<0.001)和MS组(n P0.05)；咽痛发生率3组间比较差异有统计学意义(n χ2＝7.175，n P＝0.028)，MS组(38.0%，19/50)高于SL组(18.0%，9/50，n P<0.05)和SS组(18.0%，9/50，n P0.05)。n 结论:左侧卧位I-scope气管插管用于ESD能有效优化术前麻醉时间。“,”Objective:To evaluate left lateral position I-scope tracheal intubation for optimizing anesthesia time during the patient′s general anesthesia before endoscopic submucosal dissection.Methods:A total of 150 patients with early upper gastrointestinal cancer were enrolled in the study for endoscopic submucosal dissection in Beijing Friendship Hospital, Capital Medical University from March to December 2018. Patients were randomly divided into three groups with 50 patients in each group. The SL group underwent I-scope tracheal intubation in the left lateral position, SS group underwent I-scope tracheal intubation in the supine position, and MS group underwent Macintosh laryngoscope tracheal intubation in the supine position. Preoperative non-essential anesthesia time (the time between successful intubation and operation), attempts for tracheal intubation and complications related to intubation were analyzed.Results:The preoperative non-essential anesthesia time was 8.55±2.16 min in SL group, 10.44±2.43 min in SS group, and 10.56±3.20 min in MS group, with significant difference among three groups (n F=9.08, n P<0.001), and the time in SL group was shorter than that in SS group (n P<0.001) and MS group (n P0.05). The incidence of sore throat in MS group (38.0%, 19/50) was higher than that in SL group (18.0%, 9/50,n P<0.05) and SS group (18.0%, 9/50,n P0.05).n Conclusion:I-scope tracheal intubation in the left lateral position may shorten the preoperative anesthesia time in patients undergoing general anesthesia for the operation in the left lateral position, and optimize overall anesthesia time.