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目的:分析和研究大蒜素治疗口腔溃疡的临床疗效。方法:我们选取2011年7月—2013年9月口腔溃疡患者108例,将其按双盲随机方法分为两组:观察组(54例)与对照组(54例)。对照组患者给予口服三黄片及外敷口腔溃疡散治疗;观察组患者给予大蒜素软膏外敷治疗。将两组患者治疗效果进行对比。结果:观察组患者治疗总有效率明显高于对照组(P<0.05),具有统计学意义。观察组患者复发率明显低于对照组(P<0.05),具有统计学意义。观察组患者用药治疗期间不良反应发生率明显低于对照组(P<0.05),具有统计学意义。结论:将大蒜素软膏应用于口腔溃疡患者的治疗中,药物起效快速,使用方法简单方便,患者在治疗期间没有明显的不良反应,安全可靠,并且经济实惠,利于减轻患者经济负担。
Objective: To analyze and study the clinical effect of allicin in the treatment of oral ulcer. METHODS: We selected 108 patients with oral ulcer from July 2011 to September 2013 and divided them into two groups according to double-blind randomization: observation group (54 cases) and control group (54 cases). Patients in the control group were treated with Oral Sanhuang Tablets and topical oral ulcer powder. Patients in the observation group were treated with allicin ointment externally. The treatment effect of two groups of patients were compared. Results: The total effective rate of observation group was significantly higher than that of control group (P <0.05), with statistical significance. The recurrence rate of the observation group was significantly lower than that of the control group (P <0.05), with statistical significance. The incidence of adverse reactions in observation group was significantly lower than that in control group (P <0.05), which was statistically significant. Conclusion: Allicin ointment applied to the treatment of patients with oral ulcer, the rapid onset of drugs, the use of simple and convenient method, the patient during treatment without significant adverse reactions, safe and reliable, and affordable, which will help reduce the financial burden on patients.