Mechanical Stimulus Inhibits the Growth of a Bone Tissue Model Cultured In Vitro

• 作 者: Zong-ming Wan Lu Liu Jian-yu L
• 机 构: InstituteofMedicalEquipment,DepartmentofPharmacology
• 出 处: 中国医学科学杂志：英文版
• 发表日期: 2013年4期
• 关键词: 体外生长 体外培养 机械刺激 骨组织 扫描电子显微镜 生物反应器系统 DNA梯状条带 机械负荷 bone tissue engineering mechanic
• 基金项目: Supported by grants from the National Natural Science Foundation Key Project of China （10832012） and the National Natural Science Foundation of China （31370942 and 11072266）.

Objectives To construct the cancellous bone explant model and a method of culturing these bone tissues in vitro,and to investigate the effect of mechanical load on growth of cancellous bone tissue in vitro.Methods Cancellous bone were extracted from rabbi